Wednesday, April 14, 2010

My last Blog

Hi everyone,


It is a bittersweet moment right now. I have learned so much in this class, from the different treatments to the mental affects of HIV/AIDS. I would have to say that the most interesting thing I have learned in this class is how much struggle HIV/AIDS patients goes through with the outside world compared to their physical condition. It seems that the judgment and the government makes HIV/AIDS patients life so much more difficult than it should be, which really disappoints me. Also, this class has showed me that the key to stop the spread of HIV/AIDS is education. If everyone knew about HIV/AIDS and how to protect themselves from transmission the transmission rate would drop and eventually stop.


This week has been a slow one, I wrote a post about PEP the post exposure prophylaxis and how if I was stuck with a needle while working in a health care facility I would start the regimen regardless of the side effects. I did a segment about PEP in the previous blog, and I think it is amazing that we have a sort of mourning after HIV/AIDS exposure pill. If only we could educate people about the regimen we might have a lower transmission rate too. I had absolutely no idea about PEP and I have done research on HIV/AIDS prior too, so imagine what people who have been exposed and have no idea about HIV/AIDS do. Again, I think that education is the key to eventually stopping the transmission of HIV/AIDS.


Did you Know:


This week I would like to talk about cell entry blockers, or medications that block HIV from getting in the cells in the first place. Their is a fusion inhibitor called enfuvirtide, this drug can only be injected into the bloodstream according to the Harvard Health publications. Enfuvirtide works by stopping the final stage of fusion between the HIV cell and the host cell. Another cell entry blocker is the CCR5 co-receptor antagonist called maraovic. Maraovic works by blocking chemokine receptor CCR5 which HIV uses to attach to the host's macrophages, according to the Harvard Health publications. It is amazing all of the different drugs we have for HIV/AIDS patients now and we are closer than ever to finding a cure for it.
Harvard Health Publications Mircrosoft (2010). Fighting the Virus: Treatment Options for HIV/AIDS (4.14.2010). http://www.health.msn.com/health-topics/aids-hiv/articlepage.aspx?cp-documentid=100227040

Tuesday, April 6, 2010

Almost done!

Hi everyone,

It is almost my last week here with you guys and it is a bittersweet moment. I have decided that in the next couple of semesters I am going to try and see if I can do research on if holistic remedies have any sort of effect on HIV/AIDS. Mainly I was going to see if certain herbs, and magnetic frequencies effect HIV/AIDS.
This week we were asked about if we think the Campus Confidentiality is a good idea or not. Basically, it states that if a student who is HIV positive and is having unprotected sex with someone else a health worker has the right to disclose their status. I believe it is a good idea in most situations, especially if there is proof that the student is having unprotected sex, and is trying to hide their status. However, I do believe that the workers should only disclose their status if there is absolute proof that the HIV positive student is having unprotected sex.

Also this week I attended a HIV positive panel with four different men and was shocked for so many different reasons. They all looked healthy to me and all averaged about 15 years since being diagnosed with HIV/AIDS. It shocked me that most of them only see a doctor once every four months, and there viral loads are not detectable in most cases. I see doctors more than once every four months! This has just showed me that we have come so far since the recognition of HIV/AIDS and a cure is within arms reach. I expected to see them with KS lesions or oxygen tanks and to look old, but none of them had any visual symptoms of HIV/AIDS and one guy was even a body builder. It makes me happy that HIV/AIDS is not a death sentence and with all of the medical advancements HIV/AIDS patients can live a somewhat normal life.

Did you Know:

In this weeks did you know I would like to talk about HIV drugs and resistance. HIV drugs help stop most of the replication process in HIV/AIDS, but does not kill and stop the virus all together. And according to Avert every time HIV replicates it becomes slightly better than it was before, thus becoming resistant to HIV drugs. This is noticed by the viral load increasing, and the doctor should change the drug regimen, because the pills will not effect HIV/AIDS at all. Also Avert stated that you can avoid drug resistance by taking multiple pills, taking the pills on schedule, and regularly testing the viral load. Also according to Avert drugs can have another for of resistance called cross-resistance. Cross-resistance means that if HIV is resistant to one drug it can be resistant to another drug within the same group. Cross-resistance is most common with ARVs and can limit the amount drug regimens a patient can be on. HIV drug resistant strains are very threatening and on the rise, and if we do not find a solution to this problem we will eventually have a HIV strain that is resistant to all HIV drugs.

AVERT (2010). Continuing (ARV) antiretrovial treatment. viewed (April 7, 2010). http://www.avert.org/arv-treatment.htm

Wednesday, March 31, 2010

Only a few more left

Hello everyone,

I feel bad saying this, but I am so excited this class is almost over. I am grateful for everything I have learned in this class and I am excited to use this information to further my career too. I went to Mexico last weekend and found out that you do not need a doctors prescription for pharmaceutical drugs and they are a lot cheaper to. I do not know if this is fully true or not, but the person that told me did get certain prescriptions filled. So the first thing I thought about was if HIV medications were cheaper here. It would be like a double plus cheaper medication and a trip to Mexico =D.

Also this week we were asked specifically how we would tell people, and to whom, that we were HIV positive. The first person I would tell as soon as possible whether by phone or in person would be my partner. After I got over the denial of the whole situation I would tell my family and my friends. I would tell my friends all together in a group, but only my close friends that I hope would not judge me. I would tell my close family members face to face on an individual basis, and then tell them to tell the rest of my family, because I would not be able to.

Did you know


In this weeks did you know I would like to talk about the Thai vaccine trial for HIV that is fairly new. The vaccine contains ALVAC and AIDSVAX, and were administered to groups of individuals that were at high risk, like drug users, homosexuals, and high sexual activities, and low risk. This vaccine was shown to have 31.2% efficacy. This vaccine is mainly effective for low risk patients and lasts for about a year. Although Dr. Micheal Nelson made a point in the Thai HIV Vaccine article to not take the results to heart and that it is still a trial and there is a lot of unanswered questions. I think this vaccine brings promise and I am very glad that there are scientists still working towards the cure for HIV/AIDS.




Web MD. (February 26,2010). Thai HIV Vaccine. (March 31, 2010). http://www.medscape.com/viewarticle/717677

Tuesday, March 23, 2010

Blog for week 9

Hello everyone,
Hope you all have had another amazing week. My week has been a little bit crazy and I have mainly been getting ready for a quiz coming up in this class. Last week I went over all the different tests for HIV and got tested myself a couple of weeks ago. It surprised me how many different tests there where for HIV and how they worked. To shorten it for you, the ELISA, IFA, Western Blot, OraSure, and Oraquick tests for HIV antibodies, and the PCR and Western Blot tests for viral DNA. The main test given for free most times at local health departments is the ELISA test. This test consists of HIV antibodies at the bottom of a plate and if the patients serum attaches to the plate the patient is HIV positive. One of the most expensive and accurate tests is the PCR test. The PCR test, tests for the viral DNA and can detect it even if the virus is in a latent stage and is often used to confirm ELISA results. The OraQuick and OraSure tests are basically quicker, but less accurate versions of the ELISA test. The OraQuick test is taken by blood and the OraSure test is taken through saliva. The IFA test is a stain that attach's to the HIV antibodies. Last of all the Western Blot tests for HIV antibodies and viral DNA by running the serum through the magnetized gel plate and comparing the DNA to HIVs viral DNA. It amazed me how many different tests there are for HIV. I hope that one day if HIV/AIDS is still around testing will become mandatory and free.

Also this week I was told to talk about if my grandpa contracted HIV from a nursing home what would I do about it. STDs are a major problem in the elderly community, just because someone is old does not mean they cannot be sexual. I do not know why this is, mainly I think it is because the elderly think that if they all already old whats the point of worrying anymore. Another issue is that if the elderly were HIV positive would the medication even be worth it? Depending on the side effects and the severity of the HIV/AIDS I would take the medication, but mainly just try to make the patients life as normal as possible. The elderly is a highly sexual community and a haven for STDs, and I really have no idea how to prevent it.


Did you Know
In this weeks did you know I would like to talk about PEP or Post-exposure prophylaxsis. PEP is a antiretrovial drug that is used immediately after someone has been exposed to HIV. According to avert.org PEP should be taken within 72 hours of being exposed to HIV or the chances of fighting off HIV is extremely diminsihed. PEP aims to stop HIV from becoming established in the body by helping the immune system fight it off. The most common drugs prescribed for PEP are zidovudine, lamivudine, and nelfnavir, which are also drugs that are commonly prescribed for HIV patients. This also means that patients on PEP will have side effects such as, diarrhea, headaches, nausea, and vomiting. According to advert.org patients should stay on the medication for about a month. Also according to advert.org not enough studies have been done to prove whether PEP is effective or not, but in most of the studies conducted positive results have been shown.


ADVERT (2010). What is PEP? (Veiwed March 23, 2010). http://www.advert.org/pep-prep-hiv.htm

Wednesday, March 17, 2010

Hello everyone again

Hi,

Hope everyone had an amazing spring break! It seems like it was way to short, but that is how it always is. This week is going to be a pretty long one trying to catch up on sleep and school work, especially due to the fact that are semester is closing soon. Last week we had to watch three or four movies and right different reviews on them. My favorite movie was Sliverlake Life, it was a self made documentary about a homosexual couple who both contracted HIV. The movie went over the problems with HIV/AIDS from symptoms to the publics reaction. To me they were the cutest couple ever and it was really sad when they filmed Tom dying. It showed his body being put in a bag and he was so skinny. Also, this video showed how bad the KS lesions really are, and by the end of the movie both Mark and Tom's bodies were covered in them. It was a really good movie to watch and I would recommend that you should watch it too.






Also this week we were told to wright about what we would do if we went to find a new dentist and put down that we were HIV positive and had to wait for a long time only to find out that the workers were talking out loud about are HIV condition and then tell us that the doctor was not accepting anymore patients. I would tell them to put me on the waiting list for when the doctor was accepting new patients and also ask if there were any names before me, just to be a pain since the doctor would then have to take me before he could take anymore patients. And then I would tell them that they would be hearing from my lawyers soon about the unlawful disclosure of my HIV status. It is so unacceptable that some people act this way, it is like your an outcast just because you have a disease that no one has found a cure for.

Did you Know:


In this weeks did you know I decided to research herbal remedies for HIV/AIDS patients since learning about them through the Silverlake Life movie. The main remedy I found was herbal cures. According to lifepostivie.com herbal medicine does not only help improve the immune system, but also helps fight off HIV/AIDS with certain herbs that target the disease. Also, different herbal medicines help fight off other opportunistic infections related to HIV and AIDS according to lifepositive.com. Another alternative medicine from lifepostivie.com is called HyperBaric Oxygen treatment, which involves inhaling pure, pressurized oxygen. It is supposed to help alleviate fatigue ,numbness, and other opportunistic infections from AIDS, according to lifepositive.com. It is really hard to prove if Allopathic or Holistic medicine works better mainly on the fact that there is not enough research in Holistic medicine to have hard numbers to prove its effectiveness.
References
Life Positive. (2010). Natural Treatment for HIV/AIDS. (March 16,2010). http://www.lifepositive.com/Body/body-holistic/AIDS/natural-treatment-for-aids.asp
Tom Joslin, Peter Frediman. (1993). Sliverlake Life, USA, Zeitgeist Films.

Wednesday, March 3, 2010

Hello again

Hi everyone,

Hope you all had another good week! This week has been an interesting one for me I did a lot of research on different diseases related to HIV/AIDS. One condition I researched was HIV wasting syndrome, which according to AIDS.org is, "the involuntary loss of more than 10% of body weight, plus more than 30 days of either diarrhea, or weakness and fever(aids.org, 1)." Also according to aids.org the wasting condition is caused alterations in your metabolism and hormones, and the loss of appetite due to HIV/AIDS. The second disease I researched was Kaposi's Sarcomas and according to Medline Plus they are, "a cancer that causes patches of abnormal tissue to grow under the skin, in the lining of the mouth, nose, and throat or in other organs(Medline Plus, 1)." Kaposi's Sarcomas are caused a strain of the herpes virus, herpes virus 8, because the virus brings genetic material into the cell causing too much division and growth according to Medline Plus. Another disease related to HIV/AIDS is Isosporiasis which according to aidsmeds.com is, "an organism infects the lining of the small intestine and can cause severe diarrhea and malabsorbtion (aidsmeds.com, 1)." And it is caused by the protozoan Isospora belli and is spread through feces according to aidsmeds.com. The last condition I researched was immunosuppression which according to Google Health is when the, "CD4+ count less than 200 microliter and/or CD4+ percentage of lymphocytes less than 14%(Google Health, 1)." It is caused when the body does not develop enough antibodies to help fight off a disease or foreign substance, or does not try to fight off the disease at all.

Also this week we were told to write about two different famous people that died. I have decided to wright about Robert Reed and Merritt Butrick to famous actors that died due to AIDS. Robert Reed was most remember for play the father, Mike Brady, on the Brady Bunch tv show, he was also in many other tv and movie apperances. Robert Reed was born in Illinois on October 19, 1932 and unfortunately died on May 12, 1992. Robert Reed died from colon and bladder cancer due to AIDS according to findadeath.com. Robert Reed is a well know actor and I hope that his death influenced some of the education and research movements for HIV/AIDS, but I was too young to remember. The other actor I wanted to talk about was Merritt Butrick. He was mainly known as the role of captain Kirk in Star Trek and in the movie Fright Night 2. He was born right here in Gainesville, Florida on September 3, 1959 and died on March 17, 1989. He died of AIDS when only 29 and was dedicated in a featurette during the film Square Pegs, according to findadeath.com also. It is crazy how many well know actors/actresses have died with HIV/AIDS or are still living with the condition. I hope it shows that everyone is at risk for HIV/AIDS and motivates people to help find a cure and educate for HIV/AIDS.

Did you Know

In this weeks did you know I decided to talk about a medication that helps with the HIV/AIDS related disease Kaposi's Sarcoma. According to aidsdrugsonline.com Etoposide is a medication used to treat Kaposi's Sarcoma and Aids-related non Hodgkin's lymphoma. It is also used to treat other various HIV/AIDS related cancers. It works by inhibiting the enzyme topoisomerase II and is used as a type of chemo according to aidsdrugsonline.com. Also according to aidsdrugsonline.com side effects include, "low blood pressure, hair loss, constipation, diarrhea, metallic taste in mouth, bone suppression (which lowers white cell count), and nausea(aidsdrugsonline.com, 1)." Now there was a ton more side effects on the home page, but too much for me to wright all down. One fact that surprised me was that a prescription of 28 pills cost $158.82! I do not know if insurance covers any of this medication, but I sure hope it does, because HIV/AIDS has been around long enough for the medication to be mass produced and become cheaper or covered by insurance. Also just going through the website shows you how many drugs HIV/AIDS patients have to take and the prices are through the roof, I have no idea how they afford it, because I could not now and neither could my family.

AIDS drugs. (2009). Etoposide Fact Sheet. (March 3, 2010). http://www.aidsdrugsonline.com/en/hiv-medications/etoposide

Merritt Butrick(March 3, 2010). http://www.findadeath.com/Deceased/b/merrittbutrick/johnnyslash.htm

Robert Reed(March 3, 2010). http://www.findadeath.com/Deceased/r/Robert%20Reed/robert_reed.htm

AIDS.org(2009). Wasting Syndrome(March 3, 2010). http://www.aids.org/factsheets/519-wasting-syndrome.html

Medline Plus(2009). Kaposi's Sarcoma. (March 3, 2010). http://www.nlm.nih.gov/medlineplus/kaposissarcoma.html#cat5

Aidsmeds.com(2009). Isosporosis(March 3, 2010). http://www.aidsmeds.com/articles/isosporiasis6876.shtml

Google Health(2010). Immuno deficency disorders(March 3, 2010). http://www.health.google.com/health/ref/immunodeficiency+disorders

Wednesday, February 24, 2010

My fifth week



Hi everyone,
Hope you have had another good week. This week has been pretty laid back compared to others, and mainly my week focused on finishing assignment three. I finished the book At Risk this week and was kind of disappointed about the ending. The book ended with Amanda, becoming really sick again and leaving for the hospital most likely not coming back. I do not know if the book ended right before Amanda died, or if the book ended signaling what the rest of Amanda's life would be like. Overall it was a sad book, but also an educational book. The title speaks for itself, "At Risk" it shows how not just the stereotype patients are at risk for HIV, everyone is at risk. No one asks for HIV and it is sad that it happens to unfortunate people everyday.


This weeks question had to do with saving someone who is HIV positive and risk becoming infected yourself. Mainly the story was about if you drove up to a crash and one patient had a lacerated artery and mentioned, "HIV positive" without saying if it was they were or it was the driver what would you do. In my case I would save the patient while trying my hardest to avoid contact with blood. I would probably try to use my shirt or jacket to try and stop and tie off the bleeding. Just because a person is HIV infected does not mean that their life is already over and you shouldn't try as hard to save them. A person is a person no matter what they have and if you do have an HIV patient in your lifetime just think of them as you relative, because you would wanted them to be helped just as much as a non-HIV patient. Remember no one asked to become infected with HIV and it is not their fault, so do not treat them like they did.




Did you Know:




In this weeks did you know I have decided to talk about the cures that are complete myths, but are still believed to work in Africa. Some parts of Africa still to this day believe that HIV/AIDS is more of a punishment for sins than a disease and thus do not look towards medical help. One cure that some people believe in Africa is the virgin cure, according to Science in Africa. According to Science in Africa, " Encompassed in the current belief system of both prevention/cure of HIV/AIDS is the notion that an intact hymen, and the smaller amount of vaginal secretions in young girls, prevent transmission of the disease through sexual intercourse." Also another cure Science in Africa talks about is infant rape, or the force of sexual intercourse between the age of five to eighteen months. Now I know you are all probably looking this at how horrible these people must be, but please put your judgment aside for just one second. Most of the people who believe in these cures are uneducated and the only thing they know is they will die from this curse unless they use one of the two cures. These people are not doing this, because they want to! They are because it is all they know how to do without becoming deathly sick. To me this just proves how education would be one of the main preventives of HIV/AIDS. If we could have the chance to educate everyone on what HIV/AIDS is I can guarantee that the spread of HIV/AIDS would decrease.

Wednesday, February 17, 2010

Week 4



Hello everyone,

Hope everything is well for you. Anyways this week has been full of HIV/AIDS work thanks to this class. I finished the module about the immune system and was very surprised about how advanced we are about the HIV/AIDS virus. I think that if we already know the structure and function of the virus it should not be too long before we find a way to stop it from working if not cure the virus itself. Also I finished reading my book At Risk for are assignment this week and I cried like a little baby. The last half of the book finally went into how Amanda the HIV/AIDS patient felt about the whole thing and it was the same way I would feel if I knew I was going to die. She was scared about dying and if she would be in pain, the other side, and most of all that everyone would eventually forget her. The book ended with her not dying, but getting really really sick and having to go to the hospital so one could only assume she did die. At the beginning of this week I interviewed three of my old fellow CNA students about HIV/AIDS and was in shock about how uneducated they still were about the subject. One of the questions was what stigmas they associated with HIV/AIDS and two of my friends said someone who is a sexual person, careless, and someone who abuses drugs. This was sad to me, but it just emphasizes the need for education on the subject of HIV/AIDS.




Since last week I talked about two drugs working together for a strong impact on HIV/AIDS I decided it would be best to talk about one drug that has multiple chemicals working for a strong impact on HIV/AIDS. EPZICOM is just that, it is one pill that contains both abacavir and lamivudine, which are two NRTIs. According to the HIV/AIDS article NRTI stands for Nucleoside Reverse Transcriptase Inhibitor and stops the replication of HIV by interfering with the reverse transcriptase enzyme, ultimately stopping the production of HIVs viral DNA. According to EPZICOM's homepage, "68% of patients taking a regimen with EPZICOM had their viral load become undetectable in less than one year. On top of that, patients had a 93% increase in their T-cell count." Just like the Norvir combination EPZICOM works by lowering the viral load and increasing the T-cell count, but EPZICOM is more convenient due to the fact that it is just one pill. Unfortunately, HIV can develop a drug resistance and if the patient does not recognize the problem soon enough it might be too late to start a new drug regimen in time.
Reference
ViiV Healthcare. (2010) EPZICOM Backbone Therapy. Retrieved(Feb, 15, 2010). http://www.epzicom.com/about-epzicom/backbone-hiv-therapy.html
The New York Times Company. (2010) About.com:AIDS/HIV Nucleoside Reverse Transcriptase Inhibitor (NRTI). Retrieved(Feb, 17,2010). http://aids.about.com/od/hivaidslettern/g/nrt/.htm

Wednesday, February 10, 2010

Week 3

Hello everyone,

Hope you all are having fun reading my blogs! This week I became very ill with some sort of infection similar to strep, but it is not. The doctor prescribed me a very strong antibiotic and according to my mom last time she was on it she got thrush too. Now I have a pretty week immune system and this illness is hitting me pretty hard this week, but it is opening my eyes as to how worse this infection could really get if I had no immune system. From what I have learned so far, if you have a weak immune system almost any infection can get really serious and lead to pneumonia or meningitis, which can then lead to death. This just showed me that if a HIV/AIDS patient came down with a simple virus it is not just a simple virus anymore it is a time clock. A time clock that keeps ticking away hoping you go to the doctor and get it treated fast before it turns into something worse. One important item I learned this week is that when you have HIV/AIDS every little thing in your life changes, not all for the worse, and becomes quite a bit more difficult.

Also this week we went over a question of the week which covered that Africa does not screen donated blood for HIV/AIDS like we do in the US. I was really amazed and embarrassed that I assumed that most of all Africa would screen all donated blood for HIV/AIDS, because it has been hit the hardest by it. Thankfully there are organizations out there trying to help this problem and collect money to help screen donated blood for HIV/AIDS and other viruses. One organization is the Safe Blood in Africa Foundation, which has already committed to screening one million blood units for HIV/ AIDS, Hepatitis B, Hepatitis C, and Syphilis. I really hope that soon Africa is able to screen donated blood for HIV/AIDS it would help lower the amount of people with HIV/AIDS even more and would be one step closer to stopping the spread of HIV/AIDS.

In this weeks did you know I am going to talk about a very important item in treating HIV/AIDS patients. A very big percentage of the drugs taken by HIV/AIDS patients are used in synergism. Synergism is the combining of multiple drugs to intensify their effects on a patient. The only good way I know how to explain this is say you have drug A which helps the body 1x and say you have drug B which helps the body 1x, but combined they help the body 3x.


DRUG A DRUG B A+B


1 + 1 = 3


An example of a HIV drug using synergism is Lexiva combined with Norvir. According to the Lexiva homepage it is a protease inhibitor, protease is a chemical that HIV needs to make copies of itself and Lexiva helps by blocking protease. Also according to the Lexiva homepage, Lexiva not only blocks protease, but helps your immune system by increasing your CD4T cell count. Now Norvir is used in synergy with Lexiva, according to Lexiva Norvir increases the amount of Lexiva in the body and further helps decrease the viral load and increase the immune system. Lexiva and Norvir help make HIV/AIDS manageable and is not a cure, but also helps us in finding a cure for HIV/AIDS.

References
Safe Blood for Africa Foundation(2008). Safe Blood for Africa. Retrieved(2/10/2010). http://www.safebloodforafrica.org/


ViiV Healthcare Group(2010). Lexiva. Retrieved(2/10/2010). http://www.lexiva.com/index.html






Wednesday, February 3, 2010

HIV/AIDS week two!

Hello everyone,



Hope you all are doing well this week. This week I am halfway through this book I am reading for this class. It is called At Risk by Alice Hoffman. It is about a twelve year old girl named Amanda who has AIDS due to a contaminated blood transfusion, because they were not screened. Right now in the book Amanda was just diagnosed with AIDS and the family is taking it really hard. Amanda's father Ivan is blaming her doctor and is extremely angry and aggressive. Polly, Amanda's mother is now doing everything she can possibly do to make Amanda happy and is constantly doing everything thing with the thought that Amanda does not have enough time left in the back of her head. And Charlie, Amanda's brother is mad at Amanda for ruining his life, due to the controversies AIDS is now causing at his school and between his friendship. Multiple students' parents are pulling there kids out of school in fear of their children catching AIDS and the students staying at the school and scared to use the bathroom or sit by Charlie and Amanda in fear of AIDS too. Parts of the neighbor hood are staying away, and other parts trying to help. Now, this book sets place between the 70s and 80s, and the main reason Amanda's AIDS is causing such a hysteria is due to the fact of uneducation, and unfortunately some are not educated about AIDS at all now too. This story is really eye opening to me about how tough HIV/AIDS is on a child, and it also disturbs me on how some parents in the neighborhood are acting like Amanda chose to have this disease and if she coughs on them they will catch it. This really does help show that education is one of the main factors in the prevention of the spreading of HIV/AIDS.



Also this week my class was instructed to research a HIV/AIDS organization based outside the US. My choice is the Aids foundation of South Africa (AFSA) and is the first non-government organization in South Africa. According to the AFSA website, their main focus is to improve the health to target sites by providing mentoring and support through donor's help. The AFSA also does research and reports the statistics they find.
www.aids.org/za



Did you Know:



This week I decided to talk about different HIV preventive therapies from mother to child including, HAART (Highly Active Antiretrovial Therapy), Nevirapine, and Zidovudine. HAART is used to prevent the transmission of HIV from mother to child while postnatal. According to the Science Daily HAART effectively reduces the transmission of HIV while breastfeeding up to 82%, and most of the 12% that was ineffective was, because the mothers either did not take the medicine regularly or had a too high CD4T count. Nevirapine and Zidovudine are given at the beginning of labor and up to two weeks after birth and are effective in preventing transmission up to 67%. All three of these drugs work by turning off an enzyme in HIV that prevents HIV from attaching to CD4T cells and eventually the HIV dies. It is amazing that we have such high percentages in preventing transmission from mother to child now and is sign of great things to come.



Wednesday, January 27, 2010

Did you know: HIV Vaccine "STEP" faliure

According to the Imperial London College the HIV vaccine trail know as "STEP" was halted in September of 2007 due to adverse affects. Dormant forms of HIV genes where inserted into a adenovirus shell, which we know as the common cold, in hopes that if the patient was to come into contact with the virus are body would be able to recognize the virus and fight it off. I understand that the idea was there, but the adenovirus shell did what it does best to fight off a cold. You see, when you become sick with a common cold your body increases your CD4 T-cell count especially where the virus is most likely to enter, the mucous membranes(i.e vagina, mouth, nose, and gut). Unfortunately, HIV targets CD4-T cells and uses the cells to replicate, so the vaccine just gave the patients more cells for HIV/AIDS to affect and in the most vulnerable areas too. So inadvertently, the patients taking the STEP vaccine where more likely to get infected with HIV/AIDS. I do not understand how the scientists looked past this, and honestly it seems like a pretty dumb mistake on my behalf, but we only learn by making mistakes.

Imperial College London(2009, November 19). HIV vaccine failure probably caused by virus used, says new research. ScienceDaily. www.sciencedaily.com/releases/2009/11/091116165635.htm

Tuesday, January 26, 2010

My first week with HIV simulations


http://www.aidsmap.com/

Hello everyone,

My name is Jenna, and I will be posting blogs weekly about my experience and some fun facts I have learned through my HIV/AIDS class at the University of Central Florida. This week I did two simulations to try and comprehend what HIV/AIDS patients deal with daily.
First, I did a thrush simulation to try and understand what it felt like to have thrush by inserting cotton balls into my mouth and trying to eat and drink with the cotton balls still in place. If you do not know what thrush is according to Thomason Healthcare Inc. thrush is, "a fungal infection of the oral cavity by fungi Candida, and is also know as oral Candidiasis." I have posted a picture up top of thrush too. The simulation was really eye opening for me too. The cotton balls scratched my mouth up pretty bad, and not only did I choke while trying to eat, but I drooled every time I would try to take a sip of water. Also thrush could lead to further problems like malnutrition, because who would really want to eat if it was that difficult, and the infection could spread throughout the body possibly leading to worse infections. This made it really easy for me to realize how easy day to day things could become so difficult, and how troubling it must be to live with HIV/AIDS.
Second, I did a PCP simulation(Pneumocystis Carnii Pneumonia) where I had a friend hold a pillow over my face just sightly to where it was difficult to breathe, but I would not suffocate. According to the U.S. Library of Medicine PCP is, " A pneumonia caused by the fungal organism Pneumocystis Carnii, and is also know as Pneunmocystis Jiroveci." While doing this simulation it was really uncomfortable and hard to breathe, and I cannot image what a patient would go though feeling like they could never take a full breathe without coughing up a storm. After doing this simulation I quickly realized how hard it must be for an HIV/AIDS patient to stay active or even walk a short distance. Also with PCP patients the infections can move throughout the body causing greater problems.
HIV/AIDS patients go through a lot of medical issues and I cannot imagine the mental difficulties they go through too. To have your mouth covered in a fungus that makes it difficult to eat and drink, and to most likely have a fungal infection of the lungs to where it feels like you cannot breathe half the time too. I could not imagine having to live like that it has to take a very strong person to live with HIV/AIDS and I hope to learn more about living with HIV/AIDS throughout this course.

Sources
"Oral candidiasis."CareNotes.Thomson Healthcare, Inc.,2009. Health Reference Center Academic. Web. Retrieved 11 Jan. 2010.
http://find.galegroup.com/tx.start.do?prodld=HRCA&userGroupName=lincclin_bcc.
A service of the U.S. National Library of Medicine and the National Institute of Health. (2007, November 1st). Pneumocystis carinii pneumonia. Retrieved January 14th, 2010, from http://www.nlm.nih.gov/medlineplus/ency/article/000671.htm.